Composition
Each 5ml (teaspoonful) of the Suspension and the tablet contains:
 

	Suspension (5ml)	Tablet
	200mg	400mg

Description

Evans’ Metronidazole Suspension has high activity against anaerobic bacteria and protozoa. It is a pleasantly flavoured suspension containing the equivalent of 200mg metronidazole in every 5ml.

Pharmacology

Metronidazole is used in protozoal infestations. It is also used for trichomoniasis, amoebiasis and giardiasis. Metronidazole is active against wide range of bacteria including Bacteroides spp, Anaerobic cocci, Fusobacterium spp, Clostridum spp and Gardnerella viginalis. Metronidazole is also effective against Protozoa including Trichomonas spp, Entamoeba histolytica and Giardialablia.

Indications

Treatment of Anaerobic infections, septicaemia, bacteria, puerperal sepsis, pelvic abscess, post-operative wound infections, acute dental infections, acute ulcerative gingivitis, anaerobically infected leg ulcers and pressure sores, giardiasis, trichomonal infections, non-specific vaginitis and intestinal amoebiasis.

Dosage and Administration:

Children Invasive amoebiasis: 30mg/kg daily in 3 divided doses for 8 – 10 days Giardiasis: 15mg/kg daily in divided doses for 5 - 10 days. Adult Invasive amoebiasis: 2 tablets 3 times daily for 8 – 10 days

Contraindications:

Neurological disease, blood dyscrasia, first trimester of pregnancy. Special precaution: Lactation, disulphuric like intolerance to alcohol, phenobarbitones

Side Effects:

Nausea, vomiting, unpleasant metallic taste, furred tongue and gastrointestinal disturbances; rarely, headache, drowsiness, dizziness, ataxia, darkening of urine, erythema multiforme, pruritus, urticaria, angioedema and anaphylaxis; abnormal liver function tests, hepatitis, jaundice, thrombocytopenia, aplastic anaemia, myalgia, arthralgia; peripheral neuropathy, epileptiform seizures, leukopenia, on prolonged or high dosage regimens.

Presentation

Metronidazole is available as suspension (60ml) and tablet (1000’s) .